Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel
Comprehensive genetic test evaluating key genes linked to inherited arrhythmias and cardiomyopathies. Helps clarify diagnosis, guide management, and assess familial risk.
Accessed through the Invitae Unlock™ Sponsored Testing Program•Sponsored by Invitae | Labcorp•Performed by Invitae | Labcorp
Designed to support clinical decision-making and ordering in your practice.
For healthcare providers
Overview
The Invitae Unlock™ Cardiomyopathy & Arrhythmia program offers no-charge genetic testing for U.S. patients with suspected inherited cardiomyopathy or arrhythmia. The comprehensive panel supports diagnostic clarification, risk assessment, and family variant identification. Eligible patients may access testing at no cost when ordered by a qualified healthcare provider.
When to consider this test
Patient selection
- Patient must reside in the United States.
- Patient should have clinical suspicion for a familial cardiomyopathy or inherited arrhythmia.
- Postmortem specimens are not eligible for testing under this program.
Workflow
How to use this program
- 1
Submit an order
Place the order online or via paper TRF. Include the patient’s insurance information for benefits investigation.
- 2
Collect specimen
Collect a blood, buccal, or saliva specimen using a Labcorp kit and follow standard collection procedures.
- 3
Receive results
Turnaround time is typically 10–21 days from specimen receipt. Results will be available through your Labcorp portal.
Billing overview
Program billing
For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.
Quality & privacy
Laboratory quality & data handling
Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Frequently asked questions
Which patients qualify for this program?
Eligible patients must reside in the U.S. and have clinical suspicion for an inherited cardiomyopathy or arrhythmia based on symptoms, ECG findings, imaging, or family history. Postmortem specimens are not eligible.
What does the test evaluate?
The panel includes major genes associated with inherited cardiomyopathies (e.g., TTN, LMNA, MYH7, MYBPC3, DSP, FLNC) and inherited arrhythmias (e.g., SCN5A, KCNQ1, KCNH2, RYR2, CACNA1C, CASQ2). It supports both diagnosis and family management.
How do I order the test?
Tests can be ordered online or via paper requisition. A blood, saliva, or buccal specimen may be submitted using standard collection kits.
What is the turnaround time?
Results are typically available 10–21 days after specimen receipt.
Is genetic counseling available?
Invitae provides post-result genetic counseling to patients at no additional charge. Counselors are available to review findings, provide guidance, and share relevant management resources. Providers may also request interpretation support directly.
How is billing handled?
Insurance will be billed if coverage is available. If insurance denies coverage or the patient is uninsured, a sponsored, no-charge testing pathway may be offered. De-identified patient and clinician contact information may be shared with third-party partners under this program.
Can at-risk relatives be tested?
Yes. If a pathogenic variant is identified, cascade testing may be appropriate. Follow the program’s family testing guidance as applicable.
See an issue with this program?