Invitae Epilepsy Panel
Analyzes key genes linked to syndromic and nonsyndromic epilepsy to support diagnosis, clarify prognosis, guide care, and inform family counseling.
Accessed through the Invitae Unlock™ Sponsored Testing Program•Sponsored by Invitae | Labcorp•Performed by Invitae | Labcorp
Designed to support clinical decision-making and ordering in your practice.
For healthcare providers
Overview
The Invitae Unlock Epilepsy Program provides access to the Invitae Epilepsy Panel, a 302-gene NGS panel that spans epilepsy syndromes, neurodevelopmental conditions, and metabolic and mitochondrial disorders in a single test order. It is available for patients under 18 who have presented with an unprovoked seizure. The test is billed to insurance; when a claim is denied or the patient is uninsured, Invitae covers the cost of testing, removing a common access barrier to comprehensive genomic evaluation in this population.
When to consider this test
Patient selection
- To qualify, all of the following must be met:
- Patient is currently under 18 years of age
- Patient has had an unprovoked seizure
- Available to individuals in the United States
Workflow
How to use this program
- 1
Submit an order
Place the order online or via paper TRF. Include the patient’s insurance information for benefits investigation.
- 2
Collect specimen
Collect a blood, buccal, or saliva specimen using a Labcorp kit and follow standard collection procedures.
- 3
Receive results
Turnaround time is typically 10–21 days from specimen receipt. Results will be available through your Labcorp portal.
Billing overview
Program billing
For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.
Quality & privacy
Laboratory quality & data handling
Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Frequently asked questions
Which pediatric patients are appropriate for the Invitae Unlock Epilepsy Panel?
The Invitae Unlock Epilepsy Program is available for patients under 18 who have experienced an unprovoked seizure and meet the program's eligibility criteria. The Invitae Epilepsy Panel evaluates 302 genes across epilepsy syndromes, neurodevelopmental conditions, and metabolic and mitochondrial disorders, making it suited for cases where the differential is broad or a unifying genetic diagnosis is sought.
What genes and condition categories does the Invitae Epilepsy Panel cover?
The Invitae Epilepsy Panel interrogates 302 genes via NGS, spanning epilepsy syndromes, neurodevelopmental disorders, and metabolic and mitochondrial disorders. This breadth allows a single test to address multiple diagnostic hypotheses simultaneously, supporting diagnostic confirmation, prognostic stratification, and targeted therapeutic decisions.
What specimen types are accepted for the Invitae Epilepsy Panel, and what is the turnaround time?
The Invitae Epilepsy Panel accepts whole blood, saliva, buccal swab, or extracted gDNA. Turnaround time is 10 to 21 days from specimen receipt. Testing is performed by Invitae at Labcorp.
How is the Invitae Unlock Epilepsy Program billed, and is there a prescribing obligation?
The test is billed to insurance first. If the claim is denied or the patient is uninsured, Invitae covers the cost of testing. For approved claims, billing is processed under the patient's plan as usual. Ordering through the Invitae Unlock Epilepsy Program carries no purchase or prescribing obligation of any kind.
Is genetic counseling support available through the Invitae Unlock Epilepsy Program?
The Invitae Unlock Epilepsy Program provides access to genetic counseling services. Invitae genetic counselors are available to support result interpretation and patient communication, which can be particularly useful given the breadth of the 302-gene panel and the range of epilepsy, neurodevelopmental, and metabolic conditions it covers.
How do I order the Invitae Epilepsy Panel through the Invitae Unlock program?
Orders can be placed electronically through the Invitae portal or via a paper requisition form. The program is available to licensed healthcare providers in the United States ordering on behalf of eligible pediatric patients. Specimen collection kits and ordering details are accessible through the Invitae platform.
Which patients are eligible for Invitae Unlock Epilepsy Syndromes genetic testing?
Patients may qualify for Invitae Unlock if they meet the program's eligibility criteria:
- Patients under 18 with a history of at least one unprovoked seizure.
See an issue with this program?