Sponsored diagnostic testing programs for Major Histocompatibility Complex (MHC) Class I and II Deficiencies
Major Histocompatibility Complex (MHC) Class I and II Deficiencies are rare primary immunodeficiencies caused by impaired expression of MHC molecules essential for antigen presentation. These defects severely disrupt T-cell development and immune signaling, leading to recurrent, severe infections and poor response to routine pathogens.
2 programs found for Major Histocompatibility Complex (MHC) Class I and II Deficiencies
Invitae Unlock™ Immunology provides clinicians with a comprehensive gene panel to evaluate patients with suspected primary immunodeficiency or immune-regulatory disorders. This no-charge program supports diagnostic clarification, aids in variant-guided care decisions, and can inform family cascade testing when appropriate.
Invitae Unlock Immunology offers sponsored access to the Inborn Errors of Immunity and Cytopenias Panel, Invitae’s most comprehensive assay for evaluating inherited immune disorders and cytopenias. The panel includes genes tied to combined immunodeficiencies, immune dysregulation, and bone marrow failure, supporting clearer diagnosis and management. U.S. providers may order for eligible patients.
