CardioNavigATTR (36 genes)
Covers the TTR gene plus 35 other cardiomyopathy genes to identify variant-associated risk for hereditary transthyretin amyloidosis (hATTR) and related cardiac conditions
Accessed through the NavigATTR Sponsored Testing Program•Sponsored by AstraZeneca, Ionis Pharmaceuticals•Performed by Prevention Genetics
Designed to help patients understand the purpose of testing and what to expect.
For patients
What this test and program do
This no-cost sponsored testing program provides U.S. adults access to a 36-gene hereditary cardiomyopathy panel (including the TTR gene) under the NavigATTR umbrella. The test supports evaluation of suspected hereditary transthyretin amyloidosis (hATTR) and related cardiac conditions when eligibility criteria are met.
Who this may help
Could this be right for you or your family?
- Must be a U.S. resident and 18 years of age or older.
- May qualify with a family history of hereditary transthyretin amyloidosis (hATTR), a positive PYP scan, or a biopsy consistent with amyloidosis.
- Patients with two or more red-flag symptoms suggestive of hATTR may also qualify.
- Testing must be ordered by a licensed health care professional.
What to expect
How the process works
- 1
Confirm Eligibility
Talk with your health care provider to determine whether you meet the program’s eligibility criteria and whether this test is appropriate for you.
- 2
Test Ordering
Your provider will order the test using the online portal or the program’s test requisition form.
- 3
Provide a Specimen
Your provider will collect the specimen and label it with at least two identifiers. Specimens are accepted Monday–Saturday, with holiday schedules posted in advance.
- 4
Receive Your Results
PreventionGenetics processes the test and sends results to your provider in about two weeks. Your provider will review the findings, and no-cost genetic counseling is available.
Cost & coverage
Understanding potential costs
If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.
Quality & privacy
How your sample and information are handled
Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Common questions about this program
What is this program?
The CardioNavigATTR program offers no-cost genetic testing for adults who may be at risk for hereditary transthyretin amyloidosis (hATTR) or inherited cardiomyopathy. The test analyzes 36 genes, including TTR.
Who is eligible to participate?
You must be 18 or older, live in the United States, and meet program criteria such as a family history of hATTR, a positive PYP scan, biopsy findings, or two or more red-flag symptoms.
What does the CardioNavigATTR test look for?
The test examines 36 genes linked to hereditary cardiomyopathy and hATTR. Results may help clarify whether symptoms or family history point to a genetic cause.
Is there any cost for testing?
No. The cost of genetic testing is fully covered under this sponsored program.
How long do results take?
Most results are available about two weeks after the lab receives your sample and all required paperwork.
Is genetic counseling available?
Yes. Genome Medical, a national telehealth genetics provider, offers no-cost pre-test or post-test counseling by telephone. Counseling can help you understand the test, what results mean, and what to expect. Your provider can refer you by checking the appropriate box on the requisition form.
How do I start the process?
Talk with your health care provider. They will confirm eligibility, order the test, and arrange specimen collection.
Questions to ask your doctor about CardioNavigATTR (36 genes)
- Do you think this test is appropriate for me based on my symptoms and history?
- How could the results of this test change my diagnosis or treatment plan?
- What are the potential limitations of this test that I should understand?
- Should any of my family members also be tested based on my results?
- How will we follow up after the results are available?
Notes
See an issue with this program?