X-ALD Newborn Screening Reflex Panel
A 26-gene panel assessing X-ALD and related peroxisomal disorders, including ABCD1, to support diagnosis in patients with neurologic symptoms or adrenal dysfunction.
Accessed through the Scout Sponsored Testing Program•Sponsored by Mirum Pharmaceuticals•Performed by Prevention Genetics
Designed to help patients understand the purpose of testing and what to expect.
For patients
What this test and program do
This sponsored program provides no-cost genetic testing for individuals with a positive X-ALD newborn screen or for relatives of patients diagnosed with PBD-ZSD through PreventionGenetics. Eligible patients in the U.S. can receive testing ordered by a qualified healthcare provider. The goal is to support early diagnosis and help guide medical follow-up.
Who this may help
Could this be right for you or your family?
- You screened positive for X-linked adrenoleukodystrophy (X-ALD) on a state newborn screen OR
- You are a blood relative (such as a sibling or cousin) of someone diagnosed with a peroxisomal biogenesis disorder (PBD-ZSD) through testing at PreventionGenetics
- You live in the United States
What to expect
How the process works
- 1
Check Eligibility
Your provider will confirm you meet the testing criteria and explain what the test looks for.
- 2
Order and Collect Sample
Your provider orders the test and collects a blood or buccal sample using the kit instructions.
- 3
Ship the Specimen
Follow kit instructions to label the sample with two identifiers and ship it as directed.
- 4
Get Results
Your provider receives results in about 3–4 weeks and will review them with you.
Cost & coverage
Understanding potential costs
If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.
Quality & privacy
How your sample and information are handled
Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Common questions about this program
What is this test for?
This test looks for genetic changes linked to X-linked adrenoleukodystrophy (X-ALD) and related peroxisomal conditions.
Who is eligible for testing?
Testing is available for children with a positive state newborn screen for X-ALD or blood relatives of patients diagnosed with PBD-ZSD through PreventionGenetics. You must live in the U.S.
Is the test really no cost?
Yes. If you meet eligibility criteria, the test is provided at no cost through this sponsored program.
What type of sample is required?
A blood or buccal sample may be collected, depending on your provider’s instructions and the kit received.
How long do results take?
Results are typically available about 3–4 weeks after the lab receives the specimen and required paperwork.
Is genetic counseling included?
Genetic counseling for patients and families is not included in this program. Your provider can contact PreventionGenetics genetic counselors to discuss your results.
Questions to ask your doctor about X-ALD Newborn Screening Reflex Panel
- Do you think this test is appropriate for me based on my symptoms and history?
- How could the results of this test change my diagnosis or treatment plan?
- What are the potential limitations of this test that I should understand?
- Should any of my family members also be tested based on my results?
- How will we follow up after the results are available?
Notes
See an issue with this program?