Hypoparathyroidism Panel
Analyzes 26 genes associated with inherited hypoparathyroidism to help identify genetic cause of parathyroid dysfunction and guide diagnostic evaluation.
Accessed through the DetectHypopara™ Sponsored Testing Program•Sponsored by Calcilytix Therapeutics•Performed by Prevention Genetics
Designed to support clinical decision-making and ordering in your practice.
For healthcare providers
Overview
DetectHypopara provides a sponsored, fully covered 26-gene panel targeting the genetic etiologies of hypoparathyroidism and hypocalcemia, performed by Prevention Genetics via NGS. The program, funded by Calcilytix Therapeutics, removes the cost barrier to definitive molecular diagnosis in patients whose hypoparathyroidism is non-surgical, and includes no-charge genetic counseling. Ordering carries no prescribing or purchase obligation.
When to consider this test
Patient selection
- To qualify, all of the following must be met:
- Patient is in the US
- Meets at least one of the following:
- Has a diagnosis of non-surgical hypoparathyroidism
- Has a diagnosis of idiopathic hypoparathyroidism
- Has a diagnosis of hypocalcemia suspected to be of genetic cause
- Has a relative with a diagnosis of genetic hypoparathyroidism
Workflow
How to use this program
- 1
Assess Eligibility
Review the patient’s diagnosis or clinical concern and confirm they meet residency and program criteria before discussing the test.
- 2
Order the Test
Submit the order using the appropriate U.S. TRF or Canada TRF, ensuring all necessary clinical and demographic information is complete.
- 3
Collect and Label Specimen
Collect the specimen in the correct tube and label containers with at least two identifiers. Specimens are accepted Monday–Saturday; holiday schedules apply.
- 4
Review and Discuss Results
Results are typically available about 18 days after specimen and paperwork receipt. Review findings with the patient and caregiver as appropriate.
Billing overview
Program billing
For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.
Quality & privacy
Laboratory quality & data handling
Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Frequently asked questions
Which patients are appropriate for the DetectHypopara hypoparathyroidism genetic testing program?
The DetectHypopara program is designed for patients with non-surgical or idiopathic hypoparathyroidism, hypocalcemia suspected to be of genetic origin, or a family history of genetic hypoparathyroidism. Patients must meet the program's eligibility criteria. Ordering the test carries no prescribing or purchase obligation for the clinician.
What does the DetectHypopara Hypoparathyroidism Panel cover and what methodology is used?
The DetectHypopara Hypoparathyroidism Panel interrogates 26 genes associated with genetic forms of hypoparathyroidism and hypocalcemia using next-generation sequencing (NGS). Testing is performed by Prevention Genetics, a CAP/CLIA-accredited laboratory. The full cost of the panel is covered by the sponsor, Calcilytix Therapeutics, at no charge to the patient or ordering provider.
What specimen types and collection logistics does the DetectHypopara program support?
The DetectHypopara program accepts whole blood, saliva, or OCD-100 buccal swab specimens. Sample collection kits are provided at no charge and shipped to the ordering site. This flexibility in specimen type facilitates collection across a range of clinical settings, including pediatric encounters.
What is the turnaround time for the DetectHypopara hypoparathyroidism genetic panel?
The DetectHypopara Hypoparathyroidism Panel has a turnaround time of 2 to 3 weeks from specimen receipt at Prevention Genetics. Results are returned to the ordering clinician, and the program also offers no-charge genetic counseling referrals to support results interpretation and patient communication.
Is genetic counseling included in the DetectHypopara sponsored testing program for hypoparathyroidism?
Yes, the DetectHypopara program includes no-charge genetic counseling support. Clinicians can initiate a counseling referral through the program to assist with pre-test education, results interpretation, and family implications. This service is fully covered by the program sponsor, Calcilytix Therapeutics, and carries no obligation.
Which patients are eligible for DetectHypopara Hypoparathyroidism genetic testing?
Patients may qualify for DetectHypopara if they meet the program's eligibility criteria:
- Residency: Patient resides in the U.S. or Canada.
- Clinical criteria:
- Diagnosis of non-surgical hypoparathyroidism, idiopathic hypoparathyroidism
- Hypocalcemia suspected to be genetic
- Family history of genetic hypoparathyroidism.
- Ordering requirements: Test must be ordered by a licensed health care provider.
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