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Audiology / GeneticsAuditory Neuropathy

The Resonate Program Panel

Genetic blood test evaluating nearly 300 genes associated with sensorineural hearing loss to help identify an underlying genetic cause.

Accessed through the Resonate Sponsored Testing Program•Sponsored by Akouos, Eli Lilly•Performed by Prevention Genetics

Designed to help patients understand the purpose of testing and what to expect.

For patients

What this test and program do

If you or your child has been diagnosed with auditory neuropathy or sensorineural hearing loss, finding out whether a genetic cause is involved can be an important step. The Resonate Program offers genetic testing at no cost to you, using a comprehensive panel of 274 genes to look for an underlying genetic reason for hearing loss. Understanding your results can help guide conversations with your doctors about next steps and management. The program is sponsored by Akouos and Eli Lilly, and testing is performed by Prevention Genetics, an established genetics laboratory.

Who this may help

Could this be right for you or your family?

  • In the United States (patients under 40 years old):
    • Bilateral or unilateral sensorineural hearing loss (mild, moderate, moderately severe, severe, or profound)
    • Auditory neuropathy
  • In Brazil or Mexico (patients under 18 years old):
    • Bilateral sensorineural hearing loss (severe or profound)
    • Auditory neuropathy

What to expect

How the process works

  1. 1

    Talk with your provider

    Your provider will confirm whether you meet the program’s eligibility criteria and explain how genetic testing may help you or your child.

  2. 2

    Order the test or counseling

    Your provider will review your history, confirm that you meet the program’s eligibility criteria, and explain how this genetic test may help you or your child.

  3. 3

    Provide a sample

    Your provider will either order the Resonate genetic test directly or coordinate counseling and test ordering through InformedDNA.

  4. 4

    Review your results

    The lab processes your sample and typically returns results in about 3–4 weeks. Your provider or a genetic counselor will review the findings with you.

Cost & coverage

Understanding potential costs

If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.

Quality & privacy

How your sample and information are handled

Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.

Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.

FAQ

Common questions about this program

What is the Resonate Program for auditory neuropathy and hearing loss?

The Resonate Program is a sponsored genetic testing program for people diagnosed with auditory neuropathy or sensorineural hearing loss. It uses a panel of 274 genes to help determine whether there is a genetic cause behind your hearing loss. The results can help you and your care team better understand your condition and discuss the best path forward.

Is the Resonate genetic test for auditory neuropathy really free, and who pays for it?

Yes, the Resonate Program is provided at no cost to you. There is no bill, no copay, and no insurance involvement. The program is fully funded by Akouos and Eli Lilly, so the sponsors cover the entire cost of testing.

What kind of sample is needed for the Resonate auditory neuropathy genetic test?

The Resonate Program uses a simple buccal swab, which is a gentle cheek swab. It is quick, painless, and does not require a blood draw. Your healthcare provider will collect the sample or provide you with a kit during your visit.

How long does it take to get results from the Resonate hearing loss genetic test?

Results from the Resonate Program typically take about 3 to 4 weeks after the lab receives your sample. Your ordering healthcare provider will share the results with you and can help explain what they mean for your care.

Is genetic counseling available through the Resonate Program for auditory neuropathy?

Yes, the Resonate Program includes access to genetic counseling at no cost to you. A genetic counselor can help you understand your test results, what they may mean for you or your family, and what options may be available going forward.

What happens with my information after the Resonate auditory neuropathy test?

Any data shared outside the laboratory from the Resonate Program is de-identified, meaning it cannot be traced back to you personally. This de-identified information may be used to help researchers better understand hearing loss and support the development of future treatments.

Who qualifies for Resonate Auditory Neuropathy genetic testing?

Patients may qualify for Resonate if they meet the program's eligibility criteria:

  • In the United States (patients under 40 years old):
    • Bilateral or unilateral sensorineural hearing loss (mild, moderate, moderately severe, severe, or profound)
    • Auditory neuropathy
  • In Brazil or Mexico (patients under 18 years old):
    • Bilateral sensorineural hearing loss (severe or profound)
    • Auditory neuropathy

Test details

  • ConditionAuditory Neuropathy
  • Test typeLarge NGS Panel
  • Test code16033
  • Genes / markers
    274
  • Key genes / markersGJB2, STRC, SLC26A4, TECTA, MYO15A, MYO7A, USH2A, CDH23, ADGRV1, TMC1, PCDH15, OTOF, TMPRSS3, LOXHD1, OTOA
  • Specimen
    Buccal swab
  • Turnaround time3-4 Weeks
  • LabPrevention Genetics
  • Program regionUnited States, Mexico, Brazil

Next steps

Share this information with your audiology specialist or genetic specialist. They can help determine whether this test and program are appropriate for you.

Or ask your doctor to search for this test by name at Prevention Genetics.

Questions to ask your doctor about The Resonate Program Panel

  1. Do you think this test is appropriate for me based on my symptoms and history?
  2. How could the results of this test change my diagnosis or treatment plan?
  3. What are the potential limitations of this test that I should understand?
  4. Should any of my family members also be tested based on my results?
  5. How will we follow up after the results are available?

Notes

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