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Endocrinology / GeneticsHypoparathyroidismHypocalcemia

Hypoparathyroidism Panel

Analyzes 26 genes associated with inherited hypoparathyroidism to help identify genetic cause of parathyroid dysfunction and guide diagnostic evaluation.

Accessed through the DetectHypopara™ Sponsored Testing Program•Sponsored by Calcilytix Therapeutics•Performed by Prevention Genetics

Designed to help patients understand the purpose of testing and what to expect.

For patients

What this test and program do

Living with hypoparathyroidism or unexplained low calcium can leave you with more questions than answers, especially when surgery isn't the reason. The DetectHypopara program exists to help you find out whether a genetic change is behind your condition, and it won't cost you a penny. The testing is fully covered by the program's sponsor, Calcilytix Therapeutics, and genetic counseling support is also available. Understanding the genetic basis of your condition can guide your care and give your family important information for the future.

Who this may help

Could this be right for you or your family?

  • To qualify, all of the following must be met:
    • The patient lives in the United States
    • At least one of these is true:
      • Has been diagnosed with non-surgical hypoparathyroidism (not caused by surgery)
      • Has been diagnosed with idiopathic hypoparathyroidism (no known cause)
      • Has low blood calcium (hypocalcemia) that a doctor thinks may be genetic
      • Has a blood relative diagnosed with genetic hypoparathyroidism

What to expect

How the process works

  1. 1

    Confirm Eligibility

    Talk with your health care provider to see if you meet the program criteria and whether this hypoparathyroidism genetic test is appropriate.

  2. 2

    Provider Orders Test

    Your provider will order the test using the U.S. or Canada test requisition form and guide you on next steps for specimen collection.

  3. 3

    Provide a Specimen

    Your provider will collect your specimen and label it with at least two identifiers. Specimens are accepted Monday–Saturday; holiday schedules are posted in advance.

  4. 4

    Receive Your Results

    PreventionGenetics processes your sample, and results are typically sent to your provider about 18 days after all required materials are received.

Cost & coverage

Understanding potential costs

If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.

Quality & privacy

How your sample and information are handled

Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.

Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.

FAQ

Common questions about this program

What is the DetectHypopara program for hypoparathyroidism, and what does the test look for?

The DetectHypopara program offers a genetic test called the Hypoparathyroidism Panel, which examines 26 genes that may be linked to hypoparathyroidism or genetic hypocalcemia. It is designed for people whose hypoparathyroidism was not caused by surgery, as well as those with unexplained low calcium that may have a genetic cause. The test is performed by Prevention Genetics, an established clinical laboratory.

Is the DetectHypopara genetic test for hypoparathyroidism really free, and who pays for it?

Yes, the DetectHypopara test is completely free to you. Calcilytix Therapeutics, the program's sponsor, covers the full cost of the 26-gene panel. There is no charge, no copay, and no bill sent to you or your insurance. The program also includes access to genetic counseling at no cost.

What kind of sample is needed for the DetectHypopara hypoparathyroidism genetic test?

The DetectHypopara program accepts a few different sample types, including a simple blood draw, a saliva sample, or a buccal swab (a gentle cheek swab). Your ordering clinician will help determine which option works best for you, and a collection kit is provided at no charge.

How long does it take to get results from the DetectHypopara hypoparathyroidism test?

Results from the DetectHypopara Hypoparathyroidism Panel are typically ready in about 2 to 3 weeks after the lab receives your sample. Your healthcare provider will review the findings with you and discuss what they mean for your care and your family.

Is genetic counseling available through the DetectHypopara hypoparathyroidism testing program?

Yes, the DetectHypopara program includes access to genetic counseling at no cost. A genetic counselor can help you understand your results, explain what they might mean for family members, and answer any questions you have about the testing process. Your clinician can refer you for counseling through the program.

Who qualifies for DetectHypopara Hypoparathyroidism genetic testing?

Patients may qualify for DetectHypopara if they meet the program's eligibility criteria:

  • Must reside in the United States or Canada.
  • May qualify with non-surgical hypoparathyroidism.
  • May qualify with idiopathic hypoparathyroidism.
  • May qualify with hypocalcemia suspected to be genetic in origin.
  • May qualify with a relative diagnosed with genetic hypoparathyroidism.
  • Testing must be ordered by a qualified health care provider.

Test details

  • ConditionsHypoparathyroidism, Hypocalcemia
  • Test typeTargeted NGS Panel
  • Test code15739
  • Genes / markers
    26
  • Key genes / markersCASR, GCM2, PTH, GATA3, CHD7
  • SpecimenWhole blood•Saliva•Buccal swab
  • Turnaround time2-3 Weeks
  • LabPrevention Genetics
  • Program regionUnited States, Canada

Next steps

Share this information with your endocrinologist or genetic specialist. They can help determine whether this test and program are appropriate for you.

Or ask your doctor to search for this test by name at Prevention Genetics.

Questions to ask your doctor about Hypoparathyroidism Panel

  1. Do you think this test is appropriate for me based on my symptoms and history?
  2. How could the results of this test change my diagnosis or treatment plan?
  3. What are the potential limitations of this test that I should understand?
  4. Should any of my family members also be tested based on my results?
  5. How will we follow up after the results are available?

Notes

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