The Resonate Program Panel
Genetic blood test evaluating nearly 300 genes associated with sensorineural hearing loss to help identify an underlying genetic cause.
Accessed through the Resonate Sponsored Testing Program•Sponsored by Akouos, Eli Lilly•Performed by Prevention Genetics
Designed to support clinical decision-making and ordering in your practice.
For healthcare providers
Overview
The Resonate™ program offers no-cost genetic testing for patients with sensorineural hearing loss or auditory neuropathy to support identification of genetic etiologies and inform management. De-identified data from the program may contribute to prevalence insights and therapeutic development initiatives.
When to consider this test
Patient selection
- Individuals in the United States (under 40 years of age) with at least one of the following:
- Bilateral or unilateral sensorineural hearing loss confirmed by ABR or behavioral testing (mild to profound)
- Auditory neuropathy
- Individuals in Brazil or Mexico (under 18 years of age) with at least one of the following:
- Bilateral sensorineural hearing loss confirmed by ABR or behavioral testing (severe or profound)
- Auditory neuropathy
Workflow
How to use this program
- 1
Confirm eligibility
Assess patient eligibility per country-specific criteria, review expectations for genetic testing, and discuss benefits and limitations with the family.
- 2
Order test
Order testing directly through the Resonate ordering portal or coordinate counseling and test ordering through InformedDNA for families needing additional guidance.
- 3
Collect and submit specimen
Collect the appropriate specimen and ensure containers are labeled with two identifiers. Ship to PreventionGenetics; specimens are accepted Monday–Saturday.
- 4
Review and communicate results
Results are available in 3–4 weeks from lab receipt. Review findings with the family and provide follow-up recommendations or referrals as needed.
Billing overview
Program billing
For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.
Quality & privacy
Laboratory quality & data handling
Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Frequently asked questions
Which patients are appropriate for this test?
Eligible patients include:
• U.S. individuals under 40 years with unilateral or bilateral sensorineural hearing loss (mild to profound) or auditory neuropathy; and
• Individuals under 18 years in Brazil or Mexico with severe or profound bilateral sensorineural hearing loss or a diagnosis of auditory neuropathy.
How do I order this test?
Providers may order the test via the Resonate ordering portal or refer the patient to genetic counseling at InformedDNA, who can then manage the testing logistics.
How is billing handled under the sponsored program?
The testing is sponsored and no cost to eligible patients; billing to insurance or patient responsibility does not apply when criteria are met.
Is genetic counseling required or recommended?
Genetic counseling (pre- and post-test) is strongly recommended and often facilitated via referral to InformedDNA to support testing decisions, results interpretation, and family planning.
Can these results support family testing or future management?
Yes. Identification of a pathogenic variant can inform cascade testing of at-risk relatives and tailor follow-up audiologic and genetic management for families.
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