The Resonate Program Panel
Genetic blood test evaluating nearly 300 genes associated with sensorineural hearing loss to help identify an underlying genetic cause.
Accessed through the Resonate Sponsored Testing Program•Sponsored by Akouos, Eli Lilly•Performed by Prevention Genetics
Designed to support clinical decision-making and ordering in your practice.
For healthcare providers
Overview
The Resonate Program provides no-cost access to a 274-gene NGS panel for patients presenting with auditory neuropathy or sensorineural hearing loss, enabling identification of genetic etiologies that may directly inform clinical management. Sponsored by Akouos and performed by Prevention Genetics, the program removes financial barriers to comprehensive genetic workup. Ordering carries no purchase or prescribing obligation. De-identified data from testing may contribute to prevalence research and therapeutic development.
When to consider this test
Patient selection
- Individuals in the United States (under 40 years of age) with at least one of the following:
- Bilateral or unilateral sensorineural hearing loss confirmed by ABR or behavioral testing (mild to profound)
- Auditory neuropathy
- Individuals in Brazil or Mexico (under 18 years of age) with at least one of the following:
- Bilateral sensorineural hearing loss confirmed by ABR or behavioral testing (severe or profound)
- Auditory neuropathy
Workflow
How to use this program
- 1
Confirm eligibility
Assess patient eligibility per country-specific criteria, review expectations for genetic testing, and discuss benefits and limitations with the family.
- 2
Order test
Order testing directly through the Resonate ordering portal or coordinate counseling and test ordering through InformedDNA for families needing additional guidance.
- 3
Collect and submit specimen
Collect the appropriate specimen and ensure containers are labeled with two identifiers. Ship to PreventionGenetics; specimens are accepted Monday–Saturday.
- 4
Review and communicate results
Results are available in 3–4 weeks from lab receipt. Review findings with the family and provide follow-up recommendations or referrals as needed.
Billing overview
Program billing
For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.
Quality & privacy
Laboratory quality & data handling
Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Frequently asked questions
Which patients are appropriate for the Resonate Program's auditory neuropathy and hearing loss genetic testing?
The Resonate Program is designed for patients diagnosed with auditory neuropathy or sensorineural hearing loss who meet the program's eligibility criteria. Testing is available to patients in the United States and must be ordered by a qualified healthcare provider. There is no cost to the patient; Akouos sponsors the program in full.
What does the Resonate Program panel cover and what methodology is used?
The Resonate Program Panel includes 274 genes associated with hearing loss, with TTR among the key genes evaluated. Testing is performed via next-generation sequencing (NGS) at Prevention Genetics. The breadth of the panel supports identification of a wide range of genetic etiologies underlying auditory neuropathy and sensorineural hearing loss.
What specimen type is required and what is the turnaround time for the Resonate hearing loss panel?
The Resonate Program accepts buccal swab specimens, simplifying collection in the outpatient setting without the need for phlebotomy. Turnaround time is approximately 3 to 4 weeks from specimen receipt at Prevention Genetics. Kit logistics can be coordinated through the program.
Is there any purchase or prescribing obligation when ordering through the Resonate auditory neuropathy program?
No. Ordering the Resonate Program Panel carries no purchase or prescribing obligation of any kind. The program is fully sponsored by Akouos at no cost to the patient or ordering provider. It is intended solely to support genetic diagnosis and inform clinical decision-making for patients with auditory neuropathy or sensorineural hearing loss.
Is genetic counseling included with the Resonate sensorineural hearing loss testing program?
Yes, the Resonate Program includes genetic counseling services at no charge. Counseling support is available to help contextualize results for patients and families, and to assist with discussions regarding clinical implications, family screening, and management planning.
How is patient data handled in the Resonate hearing loss genetic testing program?
Patient data shared outside of Prevention Genetics is de-identified. De-identified data from the Resonate Program may be used to support prevalence insights and therapeutic development initiatives. Individual patient information is not disclosed, maintaining standard privacy protections throughout the process.
Which patients are eligible for Resonate Auditory Neuropathy genetic testing?
Patients may qualify for Resonate if they meet the program's eligibility criteria:
- Individuals in the United States (under 40 years of age) with at least one of the following:
- Bilateral or unilateral sensorineural hearing loss confirmed by ABR or behavioral testing (mild to profound)
- Auditory neuropathy
- Individuals in Brazil or Mexico (under 18 years of age) with at least one of the following:
- Bilateral sensorineural hearing loss confirmed by ABR or behavioral testing (severe or profound)
- Auditory neuropathy
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