Invitae Fatty Acid Oxidation Defects Panel
Analyzes genes involved in mitochondrial fatty acid oxidation to evaluate suspected FAODs. Supports diagnosis when symptoms, labs, or NBS findings suggest a defect.
Accessed through the Long-Chain Fatty Acid Oxidation Disorders Sponsored Testing Program•Sponsored by Ultragenyx Pharmaceutical, Inc.•Performed by Invitae | Labcorp
Designed to support clinical decision-making and ordering in your practice.
For healthcare providers
Overview
This program gives clinicians in the US and Canada access to a comprehensive FAOD gene panel at no cost for patients with suspected LC-FAOD. The Invitae Fatty Acid Oxidation Defects Panel covers a broad set of genes involved in long-chain fatty acid transport and β-oxidation. The program supports diagnostic confirmation, personalized management, and appropriate follow-up for FAOD. There is no billing to patients, providers, or payers.
When to consider this test
Patient selection
- Ordering provider is practicing in the United States or Canada.
- Patient must meet one or more of the following:
- A completed UltraCare Start Form for LC-FAOD is available (attach any abnormal confirmatory biochemical labs when possible).
- Clinical suspicion or confirmed diagnosis of long-chain fatty acid oxidation disorder, and a plasma acylcarnitine test has been completed or ordered, irrespective of whether the result is normal or abnormal.
- Submission of available biochemical results is strongly encouraged to assist with variant interpretation.
Workflow
How to use this program
- 1
Order Test
Discuss testing with the eligible patient, obtain consent, and place the order through Invitae’s online portal.
- 2
Collect Sample
Collect the specimen using an Invitae kit and return it using the provided shipping label. Most samples ship at no additional charge from the US and Canada.
- 3
Review Results
Access results in the provider portal and review them with the patient. Invitae’s genetics experts are available to assist with interpretation.
Billing overview
Program billing
For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.
Quality & privacy
Laboratory quality & data handling
Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Frequently asked questions
Which patients qualify?
Patients in the US and Canada who either (1) have a completed UltraCare Start Form for LC-FAOD, or (2) are suspected or confirmed to have a long-chain FAOD and have had a plasma acylcarnitine test performed or ordered. Supporting lab results are encouraged when available.
Which test is performed?
The program uses Invitae’s comprehensive Fatty Acid Oxidation Defects Panel, which evaluates genes involved in mitochondrial long-chain fatty acid oxidation.
What specimens are accepted?
Invitae accepts saliva, buccal, or blood samples collected using Invitae kits. Most samples can be shipped at no additional cost from the US and Canada.
How fast are results returned?
Results are posted to the provider portal within 10–21 days after both the sample and completed TRF are received.
Is genetic counseling available for patients?
Yes. Patients in the US and Canada tested through this program receive no-charge post-test genetic counseling, provided by Invitae. Patients may schedule through their portal or by calling 1-800-436-3037.
Does participation obligate me to use sponsor products?
No. Participation does not require providers or patients to recommend, prescribe, or use any sponsor product or service.
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