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Neurology / GeneticsAmyotrophic Lateral Sclerosis (ALS)

Invitae Amyotrophic Lateral Sclerosis with C9orf72 Panel

Panel analyzes genes associated with ALS, including C9orf72 repeat expansion, the most common genetic cause. Broad testing supports diagnosis, prognosis, and counseling.

Accessed through the ALS Identified Sponsored Testing Program•Sponsored by Biogen•Performed by Invitae | Labcorp

Designed to support clinical decision-making and ordering in your practice.

For healthcare providers

Overview

The ALS Identified Program enables clinicians in the US and Puerto Rico to access a broad genetic test for patients with diagnosed or familial ALS, at no cost. This program supports diagnostic clarity, helps inform prognosis and care planning, and can facilitate family counseling or trial eligibility. All costs are covered — there is no charge to the patient, provider, or payer.

When to consider this test

Patient selection

  • Patient is 18+ and resides in the US or Puerto Rico.
  • Patient has a confirmed ALS diagnosis, or a family history of ALS, including cases where ALS appears sporadic but a hereditary cause is still possible.
  • Provider agrees to order testing as part of clinical evaluation and to counsel the patient on testing and results.

Workflow

How to use this program

  1. 1

    Order Test

    Discuss testing with the eligible patient, obtain consent, and place the order through Invitae’s online portal.

  2. 2

    Collect Sample

    Collect the patient’s specimen using an Invitae kit and return it. Use the provided label to ship most samples at no extra charge from the US and Canada.

  3. 3

    Review Results

    Receive results online and use Invitae’s resources to guide your discussion with the patient.

Billing overview

Program billing

For eligible patients, the sponsor has arrangements with the laboratory that may reduce or cover some or all of the patient's out-of-pocket cost. Actual cost and patient responsibility vary by program criteria. Refer to lab or sponsor materials for details.

Quality & privacy

Laboratory quality & data handling

Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.

Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.

FAQ

Frequently asked questions

Who is eligible for ALS Identified™ testing?

Adults (18+) residing in the US or Puerto Rico with either a confirmed ALS diagnosis or a family history of ALS, including suspected familial or apparently sporadic cases.

Which test is performed?

Testing uses Invitae’s ALS gene panel, which includes repeat expansion analysis for C9orf72, along with other genes associated with hereditary ALS.

Is there any cost to the patient or provider?

No. The program covers testing and post-test genetic counseling at no charge.

How do I order the test?

Place the order through Invitae’s online portal. Use an Invitae collection kit and return the specimen using the included prepaid label.

Are genetic counseling services included?

Yes. Patients in the US tested through the program receive no-charge post-test genetic counseling from Invitae. They can schedule directly through their patient portal or call 1-800-436-3037 for assistance.

How are results delivered?

Results are posted to the provider’s Invitae portal. Providers can use Invitae’s clinical resources to guide the interpretation and patient discussion.

Test details

  • ConditionAmyotrophic Lateral Sclerosis (ALS)
  • Test typeTargeted NGS Panel
  • Test code444002
  • Genes / markers
    22
  • Key genes / markersC9orf72, SOD1, FUS, TARDBP, TBK1
  • SpecimenWhole blood•Saliva•Buccal swab•gDNA
  • Turnaround time10-21 Days
  • LabInvitae | Labcorp
  • Program regionUnited States, Puerto Rico

Getting started

Use the links below to review program details, place orders, print requisitions, or request collection kits.

Performing lab

Invitae | Labcorp

Available in: United States, Puerto Rico

Order testPrint requisitionOrder collection kit

Privacy & ordering: This directory doesn't handle PHI. Orders occur on participating labs' systems. Privacy & Compliance

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