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Cardiology / NeurologyDanon Disease

Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel

Comprehensive genetic test evaluating key genes linked to inherited arrhythmias and cardiomyopathies. Helps clarify diagnosis, guide management, and assess familial risk.

Accessed through the Mission: Genome Sponsored Testing Program•Sponsored by Rocket Pharma•Performed by Invitae | Labcorp

Designed to help patients understand the purpose of testing and what to expect.

For patients

What this test and program do

The Mission: Genome – Danon Disease Program provides no-charge genetic testing through Invitae for individuals in the US with signs or symptoms of Danon disease. Testing evaluates the LAMP2 gene using a broad cardiomyopathy panel. Eligible patients also receive no-charge post-test genetic counseling to help understand their results.

Who this may help

Could this be right for you or your family?

  • You must live in the United States.
  • Age 40 or younger
  • Clinical suspicion of an inherited cardiomyopathy
  • Meets one or more of the following:
    • Family history of Danon disease
    • Diagnosis of cardiomyopathy not explained by acquired causes (such as medication effects or viral infection)

What to expect

How the process works

  1. 1

    Submit an order

    Your healthcare provider will place the genetic test order online or using a paper form and include your insurance information.

  2. 2

    Collect specimen

    You’ll provide a blood, saliva, or cheek swab sample using a collection kit.

  3. 3

    Receive results

    Results are typically available 10–21 days after the lab receives your sample. Your provider will review them with you.

Cost & coverage

Understanding potential costs

If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.

Quality & privacy

How your sample and information are handled

Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.

Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.

FAQ

Common questions about this program

What is the Danon Disease Program?

A no-charge genetic testing program for individuals in the U.S. under age 40 with suspected inherited cardiomyopathy, aimed at diagnosing Danon disease. Testing analyzes the LAMP2 gene via a cardiomyopathy gene panel.

Who is eligible?

Individuals in the U.S. aged 40 or younger who either have a family history of Danon disease or a diagnosis of cardiomyopathy not explained by acquired causes (e.g., not medication- or infection-related).

Is the test free for me?

Yes — if you meet eligibility criteria, testing through this sponsored program is provided at no charge.

What does the test include?

The test uses Invitae’s cardiomyopathy gene panel (or hypertrophic cardiomyopathy panel) which includes LAMP2. It is designed to detect genetic variants associated with Danon disease.

How long does it take to get results?

Results are typically available within 10–21 days from when the lab receives your sample.

Is genetic counseling included?

Yes. Patients in the U.S. tested through the program are eligible for no-charge post-test genetic counseling through Labcorp Genetics. To schedule, you can use the online portal or call 1-800-436-3037.

What if my test is positive — what happens next?

A genetic counselor and your clinician will review the result, explain what it means for your health, discuss monitoring and care recommendations, and advise on family testing or screening.

Test details

  • ConditionDanon Disease
  • Test typeNGS
  • Test code02101
  • Genes / markers
    100
  • Key genes / markersLAMP2
  • SpecimenWhole blood•Saliva•Buccal swab•gDNA
  • Turnaround time10-21 Days
  • LabInvitae | Labcorp
  • Program regionUnited States

Next steps

Share this information with your healthcare provider or genetic specialist. They can help determine whether this test and program are appropriate for you.

Or ask your doctor to search for this test by name at Invitae | Labcorp.

Questions to ask your doctor about Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel

  1. Do you think this test is appropriate for me based on my symptoms and history?
  2. How could the results of this test change my diagnosis or treatment plan?
  3. What are the potential limitations of this test that I should understand?
  4. Should any of my family members also be tested based on my results?
  5. How will we follow up after the results are available?

Notes

See an issue with this program?

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