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Cardiology / GeneticsInherited Cardiomyopathy+Inherited Arrhythmia+

Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel

Comprehensive genetic test evaluating key genes linked to inherited arrhythmias and cardiomyopathies. Helps clarify diagnosis, guide management, and assess familial risk.

Accessed through the Invitae Unlock™ Sponsored Testing Program•Sponsored by Invitae | Labcorp•Performed by Invitae | Labcorp

Designed to help patients understand the purpose of testing and what to expect.

For patients

What this test and program do

If you or a family member has been diagnosed with or is suspected of having an inherited cardiomyopathy or arrhythmia, understanding whether a genetic cause is involved can shape the care you receive and alert relatives who may also be at risk. The Invitae Unlock Cardiomyopathy and Arrhythmia Program offers a comprehensive genetic test that looks at 100 genes linked to these inherited heart conditions. The test is billed to your insurance first, and if your claim is denied or you do not have insurance, the program's sponsor covers the cost of testing so you are not left with a bill. Your healthcare provider can order the test and walk you through what the results may mean for you and your family.

Who this may help

Could this be right for you or your family?

  • To qualify, all of the following must be met:
    • The patient lives in the United States
    • A doctor thinks the patient may have an inherited heart-muscle (cardiomyopathy) or heart-rhythm (arrhythmia) condition — at least one of the following is true:
      • The patient is suspected of having, or has been diagnosed with, an inherited heart-muscle or heart-rhythm condition
      • A blood relative has been diagnosed with a heart-muscle or heart-rhythm condition
      • A blood relative died suddenly and unexpectedly from a heart-related cause that was never explained
    • Testing is ordered by a qualified healthcare provider

What to expect

How the process works

  1. 1

    Submit an order

    Your healthcare provider will place the genetic test order online or using a paper form and include your insurance information.

  2. 2

    Collect specimen

    You’ll provide a blood, saliva, or cheek swab sample using a collection kit.

  3. 3

    Receive results

    Results are typically available 10–21 days after the lab receives your sample. Your provider will review them with you.

Cost & coverage

Understanding potential costs

If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.

Quality & privacy

How your sample and information are handled

Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.

Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.

FAQ

Common questions about this program

What is the Invitae Unlock Cardiomyopathy and Arrhythmia Program?

The Invitae Unlock Cardiomyopathy and Arrhythmia Program is a sponsored genetic testing program available to patients in the United States who may have an inherited cardiomyopathy or inherited arrhythmia. It uses the Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel, which examines 100 genes associated with these inherited heart conditions. The program is designed to help clarify whether your symptoms or family history may be connected to a genetic cause, which can guide treatment decisions and alert family members who may also benefit from testing.

How does billing work for the Invitae Unlock inherited cardiomyopathy and arrhythmia genetic test?

The Invitae Unlock Cardiomyopathy and Arrhythmia Program bills your insurance first. If your insurance denies the claim, or if you do not have insurance, the program's sponsor covers the cost of testing so you are not responsible for the bill. If your insurance approves the claim, it is processed under your plan as usual, and you can direct any questions about cost-sharing to your care team.

What kind of sample is needed for the inherited cardiomyopathy and arrhythmia genetic test?

The Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel can be performed using a blood draw, a saliva sample, or a buccal (cheek) swab. Your healthcare provider will let you know which option works best for your situation. The sample is collected during a regular office visit or through a kit that your provider can arrange.

How long does it take to get results from the Invitae Unlock cardiomyopathy and arrhythmia genetic test?

Results from the Invitae Unlock Cardiomyopathy and Arrhythmia Program typically take 10 to 21 days after the lab receives your sample. Your healthcare provider will review the results with you and explain what they may mean for your treatment and for other family members who could be at risk.

Is genetic counseling available through the Invitae Unlock cardiomyopathy and arrhythmia testing program?

The Invitae Unlock Cardiomyopathy and Arrhythmia Program provides access to genetic counseling resources to help you understand your results. Genetic counselors can explain what a positive, negative, or uncertain result means for you and your family. You can ask your ordering provider about connecting with a genetic counselor before or after testing.

Can the Invitae Unlock program test for both inherited cardiomyopathy and inherited arrhythmia at the same time?

Yes. The Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel covers 100 genes associated with both inherited cardiomyopathy and inherited arrhythmia in a single test. This means your provider does not need to order separate tests for each condition, which can save time and help provide a more complete picture of your genetic risk.

Who qualifies for Invitae Unlock Inherited Cardiomyopathy genetic testing?

Patients may qualify for Invitae Unlock if they meet the program's eligibility criteria:

  • You must live in the United States.
  • You must have symptoms or a suspected diagnosis of a familial cardiomyopathy or inherited arrhythmia.
  • Postmortem testing is not available through this program.

Test details

  • Conditions
    Inherited Cardiomyopathy, Inherited Arrhythmia
  • Test typeNGS
  • Test code02101
  • Genes / markers
    100
  • Key genes / markersTTN, LMNA, MYH7, MYBPC3, TNNT2, TNNI3, DSP, PKP2, FLNC, RYR2, SCN5A, KCNQ1, KCNH2, CACNA1C, DES, TTR, GLA, LAMP2, TAZ
  • SpecimenWhole blood•Saliva•Buccal swab•gDNA
  • Turnaround time10-21 Days
  • LabInvitae | Labcorp
  • Program regionUnited States

Next steps

Share this information with your cardiologist or genetic specialist. They can help determine whether this test and program are appropriate for you.

Or ask your doctor to search for this test by name at Invitae | Labcorp.

Other Tests in This Program

Invitae Inherited Retinal Disorders Panel

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Invitae Epilepsy Panel

Invitae Unlock™•Invitae | Labcorp

Invitae Primary Immunodeficiency Panel

Invitae Unlock™•Invitae | Labcorp

Invitae Inborn Errors of Immunity and Cytopenias Panel

Invitae Unlock™•Invitae | Labcorp

Questions to ask your doctor about Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel

  1. Do you think this test is appropriate for me based on my symptoms and history?
  2. How could the results of this test change my diagnosis or treatment plan?
  3. What are the potential limitations of this test that I should understand?
  4. Should any of my family members also be tested based on my results?
  5. How will we follow up after the results are available?

Notes

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