Next Gen Krystal Biotech-l DEB SP288 Panel
No-cost genetic test analyzing key genes for epidermolysis bullosa, including COL7A1, to support diagnosis of dystrophic EB and related skin fragility disorders.
Accessed through the Decode DEB Sponsored Testing Program•Sponsored by Krystal Biotech•Performed by Prevention Genetics
Designed to help patients understand the purpose of testing and what to expect.
For patients
What this test and program do
This sponsored testing program offers no-cost genetic testing for individuals in the United States and Puerto Rico who may have epidermolysis bullosa (EB). The test helps identify the genetic cause of skin fragility and blistering symptoms. Family members of an affected individual may also qualify, even if they do not show symptoms.
Who this may help
Could this be right for you or your family?
- You must live in the United States or Puerto Rico.
- You may qualify if you have symptoms consistent with epidermolysis bullosa (EB).
- You are not eligible if you’ve already had genetic testing for EB in a clinical lab.
- Family members of an affected individual may qualify even without symptoms.
What to expect
How the process works
- 1
Check Eligibility & Learn About Testing
Your provider will confirm whether you meet the program’s eligibility criteria and explain the testing process.
- 2
Your Provider Orders the Test
Your provider will order the test using the required test requisition form.
- 3
Provide a Sample
You’ll provide a blood, saliva, or buccal sample. All samples must be labeled with two identifiers. Your provider will handle shipping.
- 4
Receive Results & Discuss Next Steps
Results are sent to your provider in about 3 weeks. Your provider will review the findings with you and may consult PreventionGenetics for interpretation support.
Cost & coverage
Understanding potential costs
If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.
Quality & privacy
How your sample and information are handled
Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Common questions about this program
What is this testing program?
This program offers no-cost genetic testing for people who may have epidermolysis bullosa (EB), a group of conditions that cause fragile skin and blistering. The test can help confirm the diagnosis and identify the specific EB subtype.
Who is eligible?
You must live in the United States or Puerto Rico. You may qualify if you have symptoms of EB or if a family member has EB and your provider recommends testing. You are not eligible if you have already had clinical genetic testing for EB.
What does the test look for?
The test analyzes multiple genes associated with EB, including COL7A1, which is linked to dystrophic EB. Identifying a genetic cause can support diagnosis and guide care.
Do I have to pay for the test?
No. The test is provided at no cost through the sponsored testing program.
How long do results take?
Results are sent to your provider about three weeks after the lab receives your sample and required paperwork.
Is genetic counseling available?
Genetic counseling services are not included with this sponsored testing program. However, your provider can consult PreventionGenetics genetic counselors to help interpret your results.
Questions to ask your doctor about Next Gen Krystal Biotech-l DEB SP288 Panel
- Do you think this test is appropriate for me based on my symptoms and history?
- How could the results of this test change my diagnosis or treatment plan?
- What are the potential limitations of this test that I should understand?
- Should any of my family members also be tested based on my results?
- How will we follow up after the results are available?
Notes
See an issue with this program?