Renasight™ Genetic Kidney Panel
Genetic test analyzing 300+ genes linked to kidney disease, helping identify inherited causes of CKD, nephrolithiasis, and related renal conditions.
Accessed through the Renasight™ Sponsored Testing Program•Sponsored by Vertex Pharmaceuticals•Performed by Natera
Designed to help patients understand the purpose of testing and what to expect.
For patients
What this test and program do
The Vertex-sponsored program provides no-cost Renasight™ genetic testing for eligible individuals of African ancestry diagnosed with chronic kidney disease. This test can identify APOL1 variants linked to APOL1-mediated kidney disease (AMKD), giving patients helpful insight into whether genetics may be contributing to their kidney condition.
Who this may help
Could this be right for you or your family?
- Patients qualify for no-charge sponsored testing if they meet all of the following:
- Self-identify as African American, African, or Afro-Caribbean
- Diagnosed with non-diabetic chronic kidney disease (CKD)
- Have no prior history of dialysis or kidney transplant
What to expect
How the process works
- 1
Confirm Eligibility
Your provider will review program criteria with you to confirm that you qualify and obtain your consent for genetic testing.
- 2
Provide a Sample
Give a blood or buccal (cheek swab) sample using a Renasight™ collection kit provided by your care team.
- 3
Receive Results
Results are typically ready in about 3 weeks. Discuss them with your provider to understand what they may mean for your kidney health.
Cost & coverage
Understanding potential costs
If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.
Quality & privacy
How your sample and information are handled
Testing is performed by Natera, a CLIA-certified laboratory (CLIA 05D1082992) and College of American Pathologists (CAP) certified laboratory (CAP 8737934). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Common questions about this program
What is this program?
This program provides no-cost genetic testing (Renasight™) for eligible patients of African ancestry to see whether APOL1 variants linked to APOL1-mediated kidney disease (AMKD) are present.
Who is eligible?
You may qualify if you:
- Identify as African American, African, or Afro-Caribbean
- Have non-diabetic chronic kidney disease (CKD)
- Have never been on dialysis and have never received a kidney transplant
Your healthcare provider will confirm your eligibility.
What does the test look for?
The test evaluates APOL1 variants, which are strongly associated with a higher risk of AMKD and faster progression of CKD in individuals of African ancestry.
What sample is required?
Your provider will collect a blood or buccal (cheek swab) sample using a Renasight™ kit.
How much does it cost?
There is no cost for eligible patients. Sponsorship is provided by Vertex Pharmaceuticals.
How long do results take?
Results are typically available in about 3 weeks.
Will I get help understanding my results?
Yes. You are eligible for no-cost post-test genetic counseling with Natera’s Renal Genetic Counselors (RGCs). They can help you:
• Understand your results and what they mean
• Learn how genetic changes may affect your health
• Discuss inheritance and family implications
Your provider also receives a summary note after your counseling session so they can incorporate it into your care plan.
Does this program determine my treatment plan?
No. Genetic testing can identify variants, including APOL1 risk alleles, but treatment decisions are made by you and your healthcare provider.
Is participation required to start or continue any treatment?
No. Participation does not obligate you to receive any specific treatment or therapy.
Questions to ask your doctor about Renasight™ Genetic Kidney Panel
- Do you think this test is appropriate for me based on my symptoms and history?
- How could the results of this test change my diagnosis or treatment plan?
- What are the potential limitations of this test that I should understand?
- Should any of my family members also be tested based on my results?
- How will we follow up after the results are available?
Notes
See an issue with this program?