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Audiology / GeneticsAuditory Neuropathy

Amplify Hearing Loss Panel

A no-cost genetic blood test analyzing 269 genes associated with childhood auditory neuropathy spectrum disorder.

Accessed through the Amplify Sponsored Testing Program•Sponsored by Regeneron•Performed by Prevention Genetics

Designed to help patients understand the purpose of testing and what to expect.

For patients

What this test and program do

The Amplify™ program provides no-cost access to genetic testing for eligible patients diagnosed with auditory neuropathy. Understanding whether a genetic factor is involved may help guide conversations with your care team about diagnosis and long-term management. Only de-identified information is shared with program partners and may support future research.

Who this may help

Could this be right for you or your family?

  • Under 18 years of age with a diagnosis or strong suspicion of auditory neuropathy.
  • Hearing evaluations showing absent or significantly abnormal ABR results.
  • Presence of otoacoustic emissions (OAEs) and/or a cochlear microphonic during testing.

What to expect

How the process works

  1. 1

    Check Eligibility

    Your provider will confirm whether you meet the program’s eligibility criteria and explain what the test looks for.

  2. 2

    Order the Test

    Your provider orders the test using the program’s test request form.

  3. 3

    Collect Your Sample

    A sample is collected using the provided tube. (Please label the tube with your name, date of birth, or ID—two identifiers are required. Samples are accepted Monday–Saturday, with holiday schedules posted one week in advance.)

  4. 4

    Test Processing

    The lab at PreventionGenetics processes your sample, and your provider receives results in about 18 days after everything is submitted. Your provider will then review and discuss the results with you.

Cost & coverage

Understanding potential costs

If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.

Quality & privacy

How your sample and information are handled

Testing is performed by Prevention Genetics, a CLIA-certified laboratory (CLIA 52D2065132) and College of American Pathologists (CAP) certified laboratory (CAP 7185561). Your sample is processed using validated methods and quality controls to support reliable genetic results.

Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.

FAQ

Common questions about this program

What does this test look for?

The Amplify™ program provides access to genetic testing for hereditary hearing loss. The test analyzes genes known to play a role in sensorineural and other inherited hearing conditions, helping your doctor understand whether your hearing differences may have a genetic cause.

Do I have to pay for this test?

Eligible patients can access testing at no cost through the Amplify™ sponsored program. There is no charge for the test itself. Your healthcare provider can confirm whether you qualify based on the program’s criteria.

How is the sample collected?

Testing is performed using a blood sample or a cheek swab, depending on your provider’s preference. Your sample is sent to PreventionGenetics, where the genetic analysis is completed in a certified clinical laboratory.

How long will it take to get my results?

Results are typically available about 18 days after the lab receives your sample and completed paperwork. Your healthcare provider will review the results with you and explain what they mean.

What will the results tell me?

Your results may help identify whether your hearing loss is associated with a genetic variant. Some results can guide medical follow-up or help inform family members about potential risks. Your doctor will interpret the findings along with your medical and family history.

Test details

  • ConditionAuditory Neuropathy
  • Test typeLarge NGS Panel
  • Test code15747
  • Genes / markers
    269
  • Key genes / markersGJB2, STRC, SLC26A4, TECTA, MYO15A, MYO7A, USH2A, CDH23, ADGRV1, TMC1, PCDH15, OTOF, TMPRSS3, LOXHD1, OTOA
  • SpecimenWhole blood•Saliva•Buccal swab
  • Turnaround time2-3 Weeks
  • LabPrevention Genetics
  • Program regionUnited States

Next steps

Share this information with your audiology specialist or genetic specialist. They can help determine whether this test and program are appropriate for you.

Or ask your doctor to search for this test by name at Prevention Genetics.

Questions to ask your doctor about Amplify Hearing Loss Panel

  1. Do you think this test is appropriate for me based on my symptoms and history?
  2. How could the results of this test change my diagnosis or treatment plan?
  3. What are the potential limitations of this test that I should understand?
  4. Should any of my family members also be tested based on my results?
  5. How will we follow up after the results are available?

Notes

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