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Explore by indication

Start from a cancer type or clinical scenario, then see associated biomarkers, therapies, and companion diagnostics.

Showing 41 IndicationsView in Know Your Companions™ →
Acute Myeloid Leukemia (AML)
Oncology • Leukemia
FLT3 (ITD/TKD) / IDH1 / IDH2
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Aggressive Systemic Mastocytosis
Oncology • Mastocytosis
KIT
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Anaplastic Thyroid Cancer (ATC)
Oncology • Thyroid
BRAF
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Astrocytoma and Oligodendroglioma
Oncology • Brain
IDH1 / IDH2
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B-cell Chronic Lymphocytic Leukemia (CLL)
Oncology • Leukemia
TP53
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Biliary Tract Cancer
Oncology • Biliary
ERBB2 (HER2)
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Breast Cancer
Oncology • Breast
BRCA1 / BRCA2 / ERBB2 (HER2) / ESR1 / PIK3CA
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Cervical Cancer
Oncology • Cervix
PD-L1
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Cholangiocarcinoma
Oncology • Bile Duct
FGFR2 / IDH1
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Chronic Myeloid Leukemia (CML)
Oncology • Leukemia
t(9;21) Philadelphia chromosome
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Colorectal Cancer (CRC)
Oncology • Colorectal
ACVR2A / BRAF / BTBD7 / DIDO1 / EGFR (HER1) / KRAS / MRE11 / NRAS / RYR3 / SEC31A / SULF2 / deficient mismatch repair (dMMR) proteins
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Duchenne Muscular Dystrophy (DMD)
Neurology • Muscle
AAV Antibodies
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Endometrial Carcinoma (EC)
Oncology • Endometrium
Not MSI-High / deficient mismatch repair (dMMR) proteins / proficient mismatch repair (pMMR) proteins
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Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Oncology • Ovary/Peritoneum
FOLR1
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Esophageal Squamous Cell Carcinoma (ESCC)
Oncology • Esophagus
PD-L1
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Follicular Lymphoma Tumor
Oncology • Lymphoma
EZH2
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Gastric and Gastroesophageal Cancer
Oncology • Stomach/GEJ
ERBB2 (HER2)
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Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Oncology • Stomach/GEJ
Claudin 18 (CLDN18) / PD-L1
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Gastrointestinal Stromal Tumors (GIST)
Oncology • GIST
PDGFRA
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Head and Neck Squamous Cell Carcinoma (HNSCC)
Oncology • Head & Neck
PD-L1
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Hemophilia A Patients
Hematology • Blood
AAV Antibodies
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Hemophilia A patients with or without factor VIII inhibitors and Hemophilia B patients with or without IX inhibitors
Hematology • Blood
Antithrombin III / Concizumab
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Low-Grade Glioma
Oncology • Brain
BRAF
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Medullary Thyroid Cancer (MTC)
Oncology • Thyroid
RET
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Melanoma
Oncology • Melanoma
BRAF
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Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Oncology • Prostate
ATM / BRCA1 / BRCA2 / Homologous recombination repair (HRR) genes
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Metastatic Colorectal Cancer (mCRC)
Oncology • Colorectal
BRAF
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Moderate to severe Hemophilia B patients
Hematology • Blood
AAV Antibodies
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Myelodysplastic Syndromes (MDS)
Oncology • Bone Marrow
IDH1 / PDGFRB
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Non-Small Cell Lung Cancer (NSCLC)
Oncology • Lung
ALK / BRAF / EGFR (HER1) / ERBB2 (HER2) / KRAS / MET / PD-L1 / RET / ROS1
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Non-Transfusion-Dependent Thalassemia
Hematology • Blood
Liver iron concentration imaging
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Obesity
Endocrinology • Metabolic
LEPR / PCSK1 / POMC
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Ovarian Cancer
Oncology • Ovary
BRCA1 / BRCA2 / HRD
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Pancreatic Cancer
Oncology • Pancreas
BRCA1 / BRCA2
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Prostate Cancer
Oncology • Prostate
BRCA1 / BRCA2
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Solid Tumors
Oncology • Solid Tumor
MSI-High / NTRK1 / NTRK2 / NTRK3 / RET / TMB / deficient mismatch repair (dMMR) proteins
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Synovial sarcoma
Oncology • Soft Tissue
HLA / Melanoma-associated antigen 4 (MAGE-A4)
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Thyroid Cancer (TC)
Oncology • Thyroid
RET
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Triple-Negative Breast Cancer (TNBC)
Oncology • Breast
PD-L1
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Urothelial Cancer
Oncology • Bladder
FGFR3 / PD-L1
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Uveal Melanoma
Oncology • Eye
HLA
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